Guidelines on red cell transfusion in sickle cell disease. Part I: principles and laboratory aspects

Blood transfusion in the management of sickle cell disease (SCD) can be lifesaving and reduces disability. However, it may cause morbidity, including alloimmunisation and iron
overload (Rosse et al, 1990; Vichinsky et al, 1990; Ballas, 2001; Darbari et al, 2006), and mortality (Royal & Seeler, 1978; Serjeant, 2003).

First published online 7 November 2016
doi: 10.1111/bjh.14346
British Journal of Haematology, 2017, 176, 179–191